Review Article C-REACTIVE PROTEIN

Abstract

C-reactive protein (CRP) is synthesized in the liver after macrophages and T-lymphocytes secrete interleukins.  It is an acute phase protein and the normal concentration ranges from 0.8 mg/L to 3 mg/L.  It is used as a marker of inflammation.  CRP levels are increased in infection, trauma, necrosis, malignancy and allergic reactions.  Patients having elevated CRP are at risk to suffer from diabetes, hypertension as well as cardiovascular disease.  CRP levels are reduced after exercise.  COVID-19 positive patients also had increased CRP levels in Wuhan, China.