Review Articles ALZHEIMER’S DISEASE (AD): MANAGING COGNITIVE IMPAIRMENTS AND BEHAVIORAL PROBLEMS

Abstract

Alzheimer’s disease being a common and multifactorial neurodegenerative disorder is one of the most challenging and emerging issues in clinical medicine these days. The current therapy includes anticholinesterases and NMDA antagonists - memantine only. Owing to the advancement in the knowledge of its pathophysiology, a lot of research is going on and many potential targets and alternative therapies including compounds acting on the pathological substrate of the disease have been proposed, which may be beneficial in prevention and treatment of this debilitating disease.