Review Articles PARKINSON’S DISEASE

Abstract

Basal ganglia (nuclei) are masses of gray matter present in the white matter of the cerebral hemisphere. These function in close association with the motor cortex and cortisospinal system. Their functions include control of corplex motor activity, cognitive control of motor activity and change of timing and extent of motor activity. Degeneration of neurons pars compacta of substantic nigra leads to Parkinson’s disease. There is deficiency of dopamine in coudate and putamen. There is imbalance between the neurotransmitter acetyl cholum & dopamine which leads to featares of the disease.